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The retromer complex safeguards against neural progenitor-derived tumorigenesis by regulating notch receptor trafficking

Single-Cell RNA Sequencing Analysis Reveals Sequential Cell Fate Transition during Human Spermatogenesis

Long-term all-optical interrogation of cortical neurons in awake-behaving nonhuman primates

BBX28 negatively regulates photomorphogenesis by repressing HY5 activity and itself undergoes COP1-mediated degradation in Arabidopsis

Multi-level genomic analyses suggest new genetic variants involved in human memory

Polyprotein strategy for stoichiometric assembly of nitrogen fixation components for synthetic biology

Single-cell RNA-seq uncovers dynamic processes and critical regulators in mouse spermatogenesis

Genome-wide maps of ribosomal occupancy provide insights into adaptive evolution and regulatory roles of uORFs during Drosophila development

Single-cell RNA-seq analysis reveals the progression of human osteoarthritis

A Genetically Encoded Fluorescent Sensor Enables Rapid and Specific Detection of Dopamine in Flies, Fish, and Mice

A genetically encoded fluorescent acetylcholine indicator for in vitro and in vivo studies

TGF-β signaling alters H4K20me3 status via miR-29 and contributes to cellular senescence and cardiac aging

Structure of the origin recognition complex bound to DNA replication origin

Global characterization of T cells in non-small-cell lung cancer by single-cell sequencing

Single-Cell RNA-Seq Reveals Dynamic Early Embryonic-like Programs during Chemical Reprogramming

The Arabidopsis USL1 controls multiple aspects of development by affecting late endosome morphology

Cryo-EM structure of human mitochondrial trifunctional protein

Single-cell multi-omics sequencing of human early embryos

A model for postzygotic mosaicisms quantifies the allele fraction drift, mutation rate, and contribution to de novo mutations

Spatial transcriptomic survey of human embryonic cerebral cortex by single-cell RNA-seq analysis